Statistics for Clinical Trials
Math 150 HW Schedule, Fall 2014
Jo Hardin
2351 Millikan
jo.hardin@pomona.edu
Office Hours: Tuesday 10am12pm, Thursday 13:30pm, or by appointment
Mentor: Yichen Lu — Monday 79pm in Millikan 1021
Text: Practicing Statistics, Kuiper & Sklar (CD information (datasets and R code) on Sakai.)
Important Dates:
 3/8/17 Midterm
 4/26/17 Research Project due (draft due earlier)
 5/11/17 Final Exam – 2pm
Handouts:
 DataCamp free R tutorial https://www.datacamp.com/courses/freeintroductiontor
 Youtube videos on getting started with R and RStudio: Introduction to RStudio
 R documentation / help
 swirl package
 Google for R: http://www.rseek.org/
 R tutorial
 An Introduction to R, Venables & Smith
 R Language Definition, R Core Team
 Another tutorial, with exercises & solutions
 Mosaic Reference Guide, need to install the mosaic package
 A Student’s Guide to R; Horton, Pruim, Kaplan (click on “Raw” to download)
 Data Wrangling Cheatsheet: http://www.rstudio.com/resources/cheatsheets/
 Clicker Questions
Date  Activity Due  HW Due  Handouts 
Wed 1/18  
Mon 1/23 
Chp 2: A1, A2, A3, A4, A5, A6 


Wed 1/25  HW #1 / Chp 2: A10, A11, A12, E1, E2, E3, E4HW 1 (R suggestions) 

Mon 1/30  Chp 6: A6, A7, A8, A17, A18 (remember that R code is on the CD for the text and on Sakai)  
Wed 2/1  HW #2 / Chp 2 & 6: 


Mon 2/6  Chp 6: A22, A23, A24 (pencil is fine, no R necessary)  Advice: knit early and often. Do NOT wait until you’ve finished the assignment to try knitting for the first time.  
Wed 2/8  HW #3 / Chp 6: E7, E11, E12 

Mon 2/13  Chp 7: A1, A2,
A3 (use R), A4


Wed 2/15  HW #4 / Chp 7: E1 (a), (b), (c); E2 no part (e); E3 no part (d) [Do the Wald tests, don’t do the likelihood ratio tests] 

Mon 2/20  Chp 7: A15 & A16  Simpson’s Paradox w logistic regression  
Wed 2/22  HW #5 / Chp 7: E1 (c); E2 (c) & (d); E3 (b), E5, E6 

Mon 2/27  nothing (read the news article)  
Wed 3/1  HW #6/Chp 7: E9 no part (d), E10 

Mon 3/6  nothing  
Wed 3/8  MIDTERM!!  NOT DUE
HW #7 / Chp 7: 
Look at handout from class to do HW 
Tuesday 10/28  Chp 9: A2 – A5  
Thursday 10/30  
Sunday 11/2  Look at handout from 10/16 & ROC handout to do project  Group Project Due 

Tuesday 11/4  
Thursday 11/6  HW #8 / Chp 9: E5, E6, A26, A27, A28  Survival in R (parts I and II)  
Tuesday 11/11  Chp 9: A37 – A42  
Thursday 11/13  HW #9 / Chp 9: E4, E11, E12, E13  
Tuesday 11/18  
Thursday 11/20  HW #10 / Chp 9: A45, A46, A47 for E11 & E12: (1) check proportional hazard assumptions for treatment KM curves, (2) use all explanatory variables and likelihood ratio test to come up with the best model 
CHD handout  
Tuesday 11/25  Read: “Why Most Published Research Findings are False”, Ioannidis  
Thursday 11/27  Thanksgiving  
Tuesday 12/2  
Thursday 12/5  HW 11 assignment .pdf , HW 11 assignment .Rnw , Dataset  
Tuesday 12/9 9:35am – 12:30pm  Final presentations – Survival analysis (Data on Sakai)  
Tuesday 12/16, noon  Individual Projects Due 