Spring 2021 – Math 150 HW

Methods in Biostatistics

Math 150, Spring 2021

Jo Hardin
2351 Estella Laboratory
jo.hardin@pomona.edu

See Sakai for all relevant links

Office Hours (on Discord, see Sakai for link):

Tuesday 8:30-9:30am PT and 3-4pm PT

Thursday 7-8am PT and 12-2pm PT

Friday 9-10:30am PT

or by appointment

Text: Practicing Statistics, Kuiper & Sklar (CD information (datasets and R code) on Sakai.)

homework assignments

Important Dates:

  • Exam 1 (date: Wednesday, March 17)
  • Exam 2 (date: Wednesday, April 28)
  • Final Data Analysis Project (date: end of semester-ish, likely Thursday May 13, draft assignments will be due earlier)

Handouts:

  • Clicker Questions
  • Linear Regression
  • Botox & Cards
  • Case Control (smoking data)
  • Log Reg tests & association (burn data)
  • Interaction & multicolinearity (HERS data)
  • Stepwise logistic regression (HERS data)
  • ROC curves (and R)  
Date Topic Section HW Due:

Friday (midnight PT) to Gradescope

Handouts / article link for class discussion Warm-ups (due by 5pm PT next day, Gradescope)
Mon 1/25 Intro       Warm-up 1: 1/25
Wed 1/27 t-tests 2.2 syllabus quiz (not an actual “quiz”): syllquiz.Rmd syllquiz.pdf just read through once (don’t need to know all the details)

Trial Design of AstraZenica

Warm-up 2: 1/27
Mon 2/1 SLR 2.3     Warm-up 3: 2/1
Wed 2/3 Fisher’s Exact Test 6.2 – 6.4 HW1 as Rmd

HW1 as pdf

  Warm-up 4: 2/3
Mon 2/8 RR & OR     What is Efficacy? Warm-up 5: 2/8
Wed 2/10 Chi-sq test 6.5 – 6.6 HW2 as Rmd

HW2 as pdf

  Warm-up 6: 2/10
Mon 2/15 Logistic regression 7.1 – 7.3   read (at minimum) the paragraph headed “Bivariate Analyses

Case-Control Study of Use of Personal Protective Measures and Risk for SARS-CoV 2 Infection, Thailand

Warm-up 7: 2/15
Wed 2/17   7.4-7.6 HW3 as Rmd

HW3 as pdf

  Warm-up 8: 2/17
Mon 2/22 Logistic regression 7.8   Obesity in Children Plummets

 

JAMA article here

(see Table 6)

we didn’t have time!
Wed 2/24   7.9 – 7.10 HW4 as Rmd

HW4 as pdf

  Warm-up 9: 2/24
Mon 3/1 Model Building     Pfizer, AstraZeneca COVID vaccines are not yet approved for kids. How are clinical trials run for children? Warm-up 10: 3/1
Wed 3/3 ROC / Cross Validation   HW5 as Rmd

HW5 as pdf

   
Mon 3/8     Spring Break    
Wed 3/10     Spring Break    
Mon 3/15 catch-up / review        
Wed 3/17     Exam 1    
Mon 3/22 Survival Analysis 9.1-9.4      
Wed 3/24 KM CI 9.5      
Mon 3/29 Log-Rank test 9.6      
Wed 3/31 Hazard Functions 9.8      
Mon 4/5 Cox PH model        
Wed 4/7 Multiple Cox PH model        
Mon 4/12 Assessing PH        
Wed 4/14 Most published research is FALSE 1.13   Why Most Published Research Findings are False“, Ioannidis, PLoS Medicine, 2005    
Mon 4/19 Multiple Comparisons        
Wed 4/21 q-values        
Mon 4/26 Stopping Criteria        
Wed 4/28     Exam 2    
Mon 5/3 Poisson regression 8 Project Viz    
Wed 5/5 Poisson regression 8 Final Project (?)    
Thurs 5/13     Final Project (?)